Skip to main content
MyPeptideDosagesMyPeptideDosages
single10MG

Kisspeptin

10MG Protocol

Kisspeptin 10MG

Injection Freq.

Inject once daily

Cycle Sched.

8–12 weeks; avoid prolonged continuous use to prevent tachyphylaxis

Reconstitution

3.0 mL BAC water

Supports physiological sex-hormone stimulation via endogenous LH/FSH signaling
Investigated for restoring fertility signaling in hypothalamic suppression contexts
Used as an ovulation-trigger concept in IVF research with potential lower OHSS risk
Generally well tolerated in cited contexts
1

Reconstitution Requirements

  • 3.0 mL BAC water
StepWeek RangeDoseUnits
1Weeks 1–2100 mcg3
2Weeks 3–8200 mcg6

Inject once daily

8–12 weeks; avoid prolonged continuous use to prevent tachyphylaxis

Kisspeptin is described as an upstream regulator of the reproductive hormone cascade. After administration, it binds kisspeptin receptors (GPR54) on GnRH neurons in the hypothalamus, triggering release of gonadotropin-releasing hormone (GnRH). GnRH then stimulates the anterior pituitary to secrete luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which act on the gonads to support sex-steroid production and gametogenesis. The protocol highlights that kisspeptin’s effects are GnRH-dependent—if GnRH release is blocked, LH/FSH stimulation does not occur—underscoring that kisspeptin works by unlocking the body’s own GnRH signaling rather than replacing it. This upstream positioning is presented as a more physiologic approach than direct GnRH or hCG use, but the page also notes that prolonged continuous exposure may lead to tachyphylaxis, supporting defined research cycles.
Mild injection-site reactions (redness/itching)
  • Use aseptic technique: wipe vial stopper with alcohol; use new sterile syringe/needle
  • Add diluent slowly down the vial wall to minimize foaming
  • Gently swirl/roll until fully dissolved (do not shake)
  • Label vial with reconstitution date and concentration; protect from light
  • Refrigerate after reconstitution (commonly 2–8 °C) unless protocol states otherwise
  • Avoid repeated freeze–thaw cycles
  • Bacteriostatic Water for Injection contains benzyl alcohol preservative (multi-dose); follow protocol for beyond-use (many peptide protocols use ~28 days after mixing)
  • Avoid benzyl-alcohol-containing diluents in neonates/infants (safety warning for benzyl alcohol)

Related peptide protocols

More research-backed dosing guides in this category.